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Andrzej Kutner Selected Research

1,25-dihydroxyergocalciferol

1/2020Synthesis, CYP24A1-Dependent Metabolism and Antiproliferative Potential against Colorectal Cancer Cells of 1,25-Dihydroxyvitamin D2 Derivatives Modified at the Side Chain and the A-Ring.
11/2016Novel analogs of 1,25-dihydroxyvitamin D2 combined with a plant polyphenol as highly efficient inducers of differentiation in human acute myeloid leukemia cells.
4/2016Differential interference of vitamin D analogs PRI-1906, PRI-2191, and PRI-2205 with the renewal of human colon cancer cells refractory to treatment with 5-fluorouracil.
10/2015Antiproliferative Activity and in Vivo Toxicity of Double-Point Modified Analogs of 1,25-Dihydroxyergocalciferol.
7/2012The pan-caspase inhibitor Q-VD-OPh has anti-leukemia effects and can interact with vitamin D analogs to increase HPK1 signaling in AML cells.
10/2008Toxicity and antitumor activity of the vitamin D analogs PRI-1906 and PRI-1907 in combined treatment with cyclophosphamide in a mouse mammary cancer model.
1/2002Side-chain modified vitamin D analogs require activation of both PI 3-K and erk1,2 signal transduction pathways to induce differentiation of human promyelocytic leukemia cells.

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Andrzej Kutner Research Topics

Disease

26Neoplasms (Cancer)
04/2022 - 09/2004
9Leukemia
04/2022 - 01/2002
7Breast Neoplasms (Breast Cancer)
03/2021 - 09/2004
7Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
11/2016 - 10/2005
6Lung Neoplasms (Lung Cancer)
01/2021 - 04/2007
6Colonic Neoplasms (Colon Cancer)
01/2019 - 02/2013
5Hypercalcemia (Milk Alkali Syndrome)
12/2021 - 11/2006
3Neoplasm Metastasis (Metastasis)
10/2019 - 06/2013
3Neuroblastoma
07/2007 - 09/2003
2Lymphoma (Lymphomas)
04/2022 - 01/2022
2Melanoma (Melanoma, Malignant)
08/2020 - 01/2016
2Colorectal Neoplasms (Colorectal Cancer)
01/2020 - 01/2019
2Osteoporosis
10/2019 - 01/2018
2Hypoxia (Hypoxemia)
01/2019 - 09/2009
2Psoriasis (Pustulosis Palmaris et Plantaris)
01/2019 - 09/2004
2Ocular Hypertension (Glaucoma, Suspect)
07/2013 - 03/2013
2Glaucoma
07/2013 - 03/2013
2Myeloid Leukemia (Leukemia, Myelocytic)
05/2010 - 10/2005
2Neurodegenerative Diseases (Neurodegenerative Disease)
11/2006 - 09/2003
1Ovarian Neoplasms (Ovarian Cancer)
12/2021
1Carcinoma (Carcinomatosis)
10/2019
1Multiple Sclerosis
01/2019
1Vitamin D Deficiency
01/2019
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
02/2018
1Secondary Hyperparathyroidism
11/2016
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
11/2016
1Nasal Polyps (Nasal Polyp)
09/2015
1Rhinosinusitis
09/2015

Drug/Important Bio-Agent (IBA)

26Vitamin DFDA LinkGeneric
01/2022 - 01/2002
23Calcitriol (Calcijex)FDA LinkGeneric
04/2022 - 01/2002
221 alpha,24-dihydroxyvitamin D3 (Tacalcitol)IBA
04/2022 - 01/2002
10calcipotriene (calcipotriol)FDA LinkGeneric
03/2021 - 04/2007
71,25-dihydroxyergocalciferolIBA
01/2020 - 01/2002
6Calcitriol Receptors (Calcitriol Receptor)IBA
01/2022 - 01/2002
6Fluorouracil (Carac)FDA LinkGeneric
01/2019 - 06/2013
5Cholecalciferol (Vitamin D3)FDA Link
04/2022 - 01/2002
5Biological ProductsIBA
01/2021 - 01/2012
4Ergocalciferols (Ergocalciferol)FDA LinkGeneric
08/2020 - 01/2002
4Imatinib Mesylate (Gleevec)FDA Link
01/2019 - 01/2012
4Cisplatin (Platino)FDA LinkGeneric
02/2018 - 09/2004
4Cytostatic AgentsIBA
02/2018 - 01/2007
4VitaminsIBA
07/2016 - 05/2014
3Pharmaceutical PreparationsIBA
04/2022 - 11/2016
3Therapeutic UsesIBA
03/2021 - 09/2007
3Hormones (Hormone)IBA
03/2021 - 11/2016
3PolyphenolsIBA
01/2021 - 07/2016
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2018 - 11/2015
2Vitamin D3 24-HydroxylaseIBA
04/2022 - 12/2021
2Proteins (Proteins, Gene)FDA Link
04/2022 - 01/2022
2Estrogens (Estrogen)FDA Link
03/2021 - 09/2003
2Sunitinib (Sutent)FDA Link
01/2019 - 02/2018
2paricalcitol (Zemplar)FDA Link
01/2019 - 11/2016
2Docetaxel (Taxotere)FDA Link
02/2018 - 01/2012
2hydroxide ionIBA
02/2018 - 01/2016
2SteroidsIBA
11/2016 - 09/2003
2Bimatoprost (Lumigan)FDA Link
07/2013 - 03/2013
21,25-dihydroxyvitamin DIBA
05/2010 - 11/2006
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
10/2008 - 09/2007
2Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
11/2006 - 09/2003
1NF-kappa B (NF-kB)IBA
04/2022
1MicroRNAs (MicroRNA)IBA
04/2022
1Messenger RNA (mRNA)IBA
12/2021
1Antineoplastic Agents (Antineoplastics)IBA
12/2021
1Aromatase (CYP19)IBA
03/2021
1Estrogen ReceptorsIBA
03/2021
1Anastrozole (Arimidex)FDA LinkGeneric
03/2021
1EnzymesIBA
03/2021
1ResveratrolIBA
01/2021
1Hydroxyl RadicalIBA
08/2020
120-hydroxyvitamin D3IBA
08/2020
1Dimethyl FumarateIBA
01/2019
1Phosphotransferases (Kinase)IBA
01/2019
1Thymidylate SynthaseIBA
01/2019
1tyrosine receptor (receptor, tyrosine)IBA
01/2019
11,3- dihydroxy- 4,4,5,5- tetramethyl- 2- (4- carboxyphenyl)tetrahydroimidazole (NOR 1)IBA
01/2019
1MineralsIBA
07/2018
1Tyrosine Kinase InhibitorsIBA
02/2018
1OsteopontinIBA
01/2018
1CollagenIBA
01/2018
1calcium phosphateIBA
11/2016
1PRI-1916IBA
07/2016
1PRI-1917IBA
07/2016
125-Hydroxyvitamin D3 1-alpha-Hydroxylase (25 Hydroxyvitamin D3 1 alpha Hydroxylase)IBA
11/2015
1Becaplermin (PDGF-BB)FDA Link
11/2015
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
11/2015
1Timolol (Blocadren)FDA LinkGeneric
07/2013
1tafluprostIBA
07/2013
1Travoprost (Travatan)FDA Link
07/2013
1Latanoprost (Xalatan)FDA Link
07/2013
1Capecitabine (Xeloda)FDA Link
06/2013
1Prostaglandins FIBA
03/2013
1Mitogen-Activated Protein Kinase 3IBA
02/2013
1Oxaliplatin (Eloxatin)FDA LinkGeneric
02/2013
1Irinotecan (Camptosar)FDA LinkGeneric
02/2013
1CarbonIBA
09/2012
1quinoline-val-asp(OMe)-CH2-OPHIBA
07/2012

Therapy/Procedure

13Therapeutics
10/2019 - 09/2004
3Drug Therapy (Chemotherapy)
10/2019 - 06/2016
2Aftercare (After-Treatment)
01/2019 - 08/2014
1Treatment Delay
01/2018